Mirtazapine belongs to a class of drugs called antidepressants. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. It may increase the amounts of norepinephrine and serotonin in your brain.
These are chemical messengers that affect your mood. Mirtazapine oral tablet may cause drowsiness. It may affect your ability to make decisions, think clearly, or react quickly. You may feel restless and agitated unable to sit or stand still for the first few weeks while taking this drug.
If these effects are mild, they may go away within a few days or a couple of weeks. Call your doctor right away if you have serious side effects.
Serious side effects and their symptoms can include the following:. Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects.
This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history. Mirtazapine oral tablet can interact with other medications, vitamins , or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully.
Taking certain drugs with mirtazapine may cause serious side effects. These drugs include:. Taking it again could be fatal cause death. The use of drinks that contain alcohol can increase your risk of sleepiness from mirtazapine. This may affect your ability to make decisions, think clearly, or react quickly. If you drink alcohol, talk to your doctor. For people with a history of mania or bipolar disorder : Talk to your doctor about whether this drug is safe for you.
Mirtazapine may trigger a mixed or manic episode. For people with seizures: Talk to your doctor about whether this drug is safe for you. This drug may make your condition worse. If you have a seizure while taking mirtazapine, talk to your doctor. They will decide if you should stop taking it. You may need to stop taking this drug right away, or your dosage may slowly be lowered over time to avoid withdrawal symptoms. For people with heart problems: If you have a history of certain heart problems, talk to your doctor about whether this drug is safe for you.
These heart problems include angina chest pain , heart attack , or stroke. Mirtazapine can cause low blood pressure, which can make heart problems worse. For people with glaucoma or other eye problems: This drug may dilate your pupils. This may trigger a glaucoma attack. Before you take this drug, tell your doctor if you have glaucoma.
For people with kidney problems: If you have kidney problems or a history of kidney disease, you may not be able to clear this drug from your body well. This may increase the amount of mirtazapine in your body and cause more side effects. For people with liver problems: If you have liver problems or a history of liver disease, you may not be able to process this drug as well. For pregnant women: Mirtazapine is a category C pregnancy drug. That means two things:.
Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own. Your healthcare provider will want to see you often while you are taking mirtazapine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.
The doctor or pharmacist will give you the manufacturer's patient information sheet Medication Guide when you begin treatment with mirtazapine. Read the information carefully and ask your doctor or pharmacist if you have any questions. No matter what your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments.
You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder mood that changes from depressed to abnormally excited or mania frenzied, abnormally excited mood or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history.
You and your doctor will decide what type of treatment is right for you. Mirtazapine is used to treat depression. Mirtazapine is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain to maintain mental balance. Mirtazapine comes as a tablet and as a disintegrating tablet to take by mouth. It usually is taken once a day at bedtime.
It may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take mirtazapine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
To take a mirtazapine disintegrating tablet, open the blister pack with dry hands and place the tablet on your tongue. The tablet will disintegrate on the tongue and can be swallowed with saliva. No water is needed to swallow disintegrating tablets. Once the tablet is removed from the blister pack, it cannot be stored.
Do not split mirtazapine disintegrating tablets. It may take several weeks or longer for you to feel the full benefit of mirtazapine. Continue to take mirtazapine even if you feel well. Do not stop taking mirtazapine without talking to your doctor. The amount of mirtazapine that can lead to an overdose varies from person to person.
If you've taken too much mirtazapine you may experience symptoms such as:. Take the mirtazapine packet, or the leaflet inside it, plus any remaining medicine with you. Like all medicines, mirtazapine can cause side effects in some people, but many people have no side effects or only minor ones. Some of the common side effects of mirtazapine will gradually improve as your body gets used to it.
Serious side effects are rare and happen in less than 1 in 10, people when taking mirtazapine. In rare cases, it's possible to have a serious allergic anaphylaxis reaction to mirtazapine. You could be having a serious allergic reaction and may need immediate treatment in hospital. These are not all the side effects of mirtazapine.
For a full list, see the leaflet inside your medicine packet. You can report any suspected side effect to the UK safety scheme. It's important for you and your baby that you stay well during your pregnancy. If you become pregnant while taking mirtazapine speak to your doctor. Do not stop taking your medicine unless your doctor tells you to. Mirtazapine has been linked to a very small increased risk of problems for your unborn baby.
But if your depression is not treated during pregnancy this can also increase the chance of problems. You may take mirtazapine during pregnancy if you need it to remain well. Your doctor can explain the risks and the benefits, and will help you decide which treatment is best for you and your baby. For more information about how mirtazapine can affect you and your baby during pregnancy, read the leaflet about the best use of medicines in pregnancy BUMPS.
If your doctor or health visitor says your baby is healthy, mirtazapine can be used during breastfeeding. It has been used by many breastfeeding mothers usually without any problems. Mirtazapine passes into breast milk in small amounts. It has been linked with side effects in very few breastfed babies. It's important to continue taking mirtazapine to keep you well. Breastfeeding will also benefit both you and your baby. If you notice that your baby isn't feeding as well as usual, or seems unusually sleepy, or if you have any other concerns about your baby, talk to your health visitor or doctor as soon as possible.
Some medicines and mirtazapine can interfere with each other and increase the chances of you having side effects. Do not take St John's wort while you are being treated with mirtazapine as this will increase your risk of side effects.
Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements. It works by increasing the activity of mood-enhancing chemicals called noradrenaline and serotonin in the brain. You may see an improvement in your symptoms after a week although it usually takes between 4 and 6 weeks before you feel the full benefits.
That's because it takes around a week for mirtazapine levels to build up in your body, and then a few weeks longer for your body to adapt and get used to it. Do not stop taking mirtazapine just because you feel it is not helping your symptoms. Give the medicine at least 6 weeks to work.
Antidepressants like mirtazapine help to gradually lift your mood so you feel better. You may notice that you sleep better and get on with people more easily because you're less anxious. You will hopefully take things that used to worry you in your stride.
Mirtazapine won't change your personality or make you feel euphorically happy. It will simply help you feel like yourself again. Don't expect to feel better overnight, though.
Some people feel worse during the first few weeks of treatment before they begin to feel better. Once you're feeling better you're likely to keep taking mirtazapine for several months.
Most doctors recommend that you take antidepressants for 6 months to a year after you no longer feel depressed. Stopping your medicine too soon can make depression come back. Most doctors recommend taking antidepressants for 6 to 12 months after you stop feeling depressed. Mirtazapine is generally safe to take for a long time. There don't seem to be any lasting harmful effects from taking it for many months and years. If you've been feeling better for 6 months or more, your doctor may suggest coming off mirtazapine.
Your doctor will probably recommend reducing your dose gradually over several weeks, or longer if you've been taking mirtazapine for a long time. This is to help prevent you getting any extra side effects as you come off the medicine. Do not stop taking mirtazapine suddenly, or without talking to your doctor first.
Mirtazapine isn't any better or worse than other antidepressants.
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